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1999-2003年发表的论文 (525篇) 之五

  • 关键字: 1999-2003年发表的论文 (525篇) 之五 发布者:宣传部 发布时间:2008-12-18 09:12:41 点击数: 2655次

1999年-2003年发表的论文

    自上次评估1999年7月到2004年3月,生命有机国家重点实验室在科技部、国家自然科学基金委员会、中国科学院、上海市科委以及依托单位上海有机化学研究所的大力支持下,经过全体科研人员的努力,做出了一些在国际上有一定影响的成绩。共发表论文525篇,其中在Acc. Chem. Res., PNAS, Angew. Chem. Int. Ed., J. Am. Chem. Soc.等影响因子大于5的杂志上发表论文10篇,在影响因子为3到5之间的杂志上发表论文为76篇,在影响因子为23之间的杂志上的论文为131篇。实验室在如下5个方面取得了具有代表性阶段性成果:

 

  1. 具有抗癌、抗炎和抗疟活性的复杂天然产物的合成,结构-活性关系及作用机制研究方面的论文

  2. 一些生物大分子的选择性小分子调节剂的设计、合成及活性研究方面的论文

  3. 有机合成新反应和新方法的研究以及它们在复杂生物活性分子合成中的应用方面的论文

  4. 生物催化和生物转化方面的论文

  5. 酶和细胞色素等蛋白质的结构生物学研究方面的论文

     

 

5.酶和细胞色素等蛋白质的结构生物学研究方面

论文24篇及他引数45次

 

序号

论 文 名 称

作 者

刊物名称

年卷

期页

他引

次数

1

Structure, Interaction and Electron Transfer Between Cytochrome b5, its E44A and/or E56A Mutants and Cytochrome c

Y. Sun#, Y.Wang#, M.Yan#, B. Sun#,Y. Xie#, Z.Huang#

, S. Jiang, H. Wu

J. Mol. Biol.

1999

,285, 347-359

4

2

Detailed Active Site Configuration of a New Crystal Form of Methanol Dehydrogenase from Methylophilus W3A1 at 1.9Å Resolution

Z. Xia,Y. He, W.Dai#, S. A. White#,G. D. Boyd#,F. S. Mathews#

Biochemistry

1999

, 38, 1214- 1220

22

3

Effect of Mutation at Valine 61 on the Three- Dimensional Structure, Stability, and Redox Potential of Cytochrome b5

L. Xue#, Y.Wang#,Y. Xie#, P.Yao#, W.Wang#,W. Qian#, Z.Huang#

, J Wu, Z. Xia

Biochemistry

1999

, 38, 11961-11972

8

4

Three-dimensional structure of b-momor- charin at 2.55Å resolution

Y. Yuan,Y. He,J. Xiong

,Z. Xia

Acta Cryst.D, Biol.Cryst.

1999

, D55, 1144- 1151

2

5

Purification and characterization of trichomaglin - A novel ribosome- inactivating protein with abortifacient activity

R Chen

, Y. Xu,J Wu, Z Pu#,S. Jin, W.Liu#, Z. Xia

Biochem. and Mol. Biol. International

1999

185- 193

, 47,

 

6

Crystal Structures of the Complexes of Tricho- santhin with Four Substrate Analogs and Catalytic Mechanism of RNA N-Glycosidase

Y. Gu

Z. Xia

,

PROTEINS:
Structure, Function, and Geneics

2000

, 39, 37-46
 

7

Crystal Structure of Recombinant Trypsin- Solubilized Fragment of Cytochrome b5 and the Structural Comparison With Val61His Mutant

J. Wu, J. Gan

, Z.Xia, Y.Wang#, L. Xue#,.Z. Huang#

PROTEINS:
Structure,
Function, and

Geneics

2000

249- 257

, 40,

1

8

Adenine Nucleotide N-Glycosidase Activity of the A-Chain of Cinnamomin Characterized by 1H-Nuclear Magnetic Resonance

Y. Xu

#,Y. Li,H. Hu#,R. Hu#,H. Wu, W. Liu#

Biol. Chem.

2000

,381, 447-451
 

9

Solution Structure of BmPO1 from the Venom of Scorpion Buthus martensii Karsch

G. Wu, Y. Li

,D. Wei#, F. He,S. Jiang,G. Hu#, H. Wu

Biochem. and Biophys. Res. Commun.

2000

, 276, 1148-1154
 

10

Crystallization and preliminary crysyallo-graphic studies of trichomaglin, a novel ribosome- inactivating protein

J. Wu, J. Gan

, Z. Xia

Acta Cryst. D,Biol. Cryst.

2000

, D56, 1466- 1467
 

11

Overexpression in Escherichia coli and Cha- racterization of the Chloroplast Fructose-1,6- biphosphatase from Wheat

G. Tang

, Y. Wang#, J. Bao#, H. Chen

Protein Ex- pression and

Purification

2000

, 19, 411- 418
 

12

Molecular Modeling of the Interactions of Trichosanthin with Four Substrate Analogs

Y. Gu

, W. Chen,Z. Xia

J. Protein

Chem.

2000

, 19, 291- 297
 

13

Catalytic mechanism of quinoprotein metha-nol dehydrogenase: A theoretical and x-ray crystallo- graphic investigation

Y. Zheng

#Z. Xia Z. Chen# F. S. Mathews# T. C. Bruice#

Proc. Natl.

Acad. Sci.USA

2001

, 98, 432- 434

5

14

Properties of Hybrid Enzymes between Syne- chococcus Large Subunits and Higher Plant Small Subunits of Ribulose-1,5-bisphosphate Carboxylase/ Oxygenase in Escherichia col

Y. Wang,J.Zhou

, Y. Wang#,J. Bao#,H. Chen

Archives of

Biochem.and
Biophys.

2001

, 396, 35-42

3

15

Two-Cistron System Overexpression of Chlo- roplast Glyceraldehyde-3- phosphate Dehydroge- nase Subunit B and B-Derivatives from Spinach in Escherichia coli

G. Tang

J. Bao#H. Chen

Y. Wang#

Protein
Expression
and

Purification

2001

, 22, 31-37
 

16

X-ray crystallography, circular dichroism and kinetic studies revealed the essence of the abnormal behaviors of cytochrome b5 Phe35Tyr Mutant

P. Yao,# J. Wu, Y. Wang,#B.Sun,

#Z. Xia, Z. Huang#

Eur. J.

Biochem.

2002

, 269, 4287-4296
 

17

Crystal Structures of V45E and V45Y Mutants and Structure Comparison of a Variety of Mutants of Cytochrome b5

J. Gan, J. Wu

, Z. Wang,#Y. Wang#,Z. Huang,#Z-X Xia

Acta Cryst.

2002

, D58, 1298-1306
 

18

X-ray structure of methanol dehydrogenase from Paracoccus denitrificans and molecular modeling of its interactions with cytochrome c-551i

 

Z. Xia,W. Dai, Y. He,S. A. White#,F. S. Mathews#,V. L. Davidson#

J. Biol. Inorg. Chem.

2003

843-854

, 8,
 

19

1

H NMR studies of the effect of mutation at Valine45 on heme microenvironment of cyto- chrome b5

C. Cao, Q. Zhang

,Z. Wang#, Y. Wang, Y. Wang#, H. Wu, Z. Huang#

Biochimie

2003,

85, 1007-1016
 

20

Solution structure and biological activity of recombinant salmon calcitonin S-sulfonated analog

Y. Wang, H

.Dou,C. Cao, N. Zhang, J. Ma, J. Mao,H.Wu

Biochem.and Biophys. Res.Commun.

2003

, 306, 582-589
 

21

The solution structure of the oxidized bovine microsomal cytochrome b5 mutant V61H

C. Cao,Q. Zhang,L. Xue#, J. Ma,Y. Wang#

, H-M Wu, Z. Huang#

Biochem.and Biophys. Res.Commun.

2003,

307, 600- 609
 

22

BmKK4, a novel toxin from the venom of Asian scorpion Buthus Martensi Karsch, inhibits potassium currents in rat hippocampal neurons in vitro

M. Li#, N. Zhang, X. Chen, G. Wu

, H.Wu, G. Hu#

Toxicon

2003,

42, 199- 205
 

23

Crystallization and preliminary crystallographic study of rBmk

?? IT1, a recombinant ?-insect toxin from the scorpion Buthus Martensii Karsch

Y Huang.

, Q. Huang,# H. Chen, Y.Tang,# H.Miyake,#M. Kusunoki#

Acta Cryst.

2003

, D59, 1635-1636
 

24

Crystallization and preliminary crystallographic studies of Escherichia coli CcmG/DsbE protein

N Ouyang,

W. Chen, Q Li,Y. GaoH. Hu, Z. Xia

Acar Cryst

2003,

D59, 1674-1675
 

 

成果5前期研究工作部分论文4篇及其引用数134次情况

 

1

Crystal-Stucture of Trichosanthin-NADPH at 1.7 Angstrom Resolution Reveals Active-site Archi-tecture

J. Xiong

, Z. Xia,Y. Wang

Nature Structural Biology

1994,

659-700

1,

21

2

1,3-Dipolar Cycloaddition Reaction of [60] Fullerene and Imines of a-Amino Acid Esters: Formation of Fullerene- fused Proline Derivatives

L. Shu, G. Wang, S. Wu

, H.Wu ,X. Lao

Tetrahedron Lett.

1995

,36, 3871-3874,

29

3

Determination of the gene sequence and the three-dimensional structure at 2.4 angstrom reso- lution of methanol dehydrogenase from Methylo- philus W3A1

Z. Xia, W. Dai,Y. Zhang, S. A. White, G. D. Boyd, F.S.Mathews

J. Mol. Biol.

1996,

480-501

259,

63

4

Inclusion complexation of (cyclo)- alkanes and (cyclo)alkanols with 6-O- modified cyclodextrins

Y. Inoue,K. Yamamoto, T. Wada, S.veritt, X.Gao,Z.Hou, L.Tong, S. Jiang

, H.Wu

J.Chem.Soc.

Perkin
Trans 2

1998,

1807-1816

21