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1999-2003年发表的论文 (525篇) 之四

  • 关键字: 1999-2003年发表的论文 (525篇) 之四 发布者:宣传部 发布时间:2008-12-18 09:12:02 点击数: 2449次

1999年-2003年发表的论文

    自上次评估1999年7月到2004年3月,生命有机国家重点实验室在科技部、国家自然科学基金委员会、中国科学院、上海市科委以及依托单位上海有机化学研究所的大力支持下,经过全体科研人员的努力,做出了一些在国际上有一定影响的成绩。共发表论文525篇,其中在Acc. Chem. Res., PNAS, Angew. Chem. Int. Ed., J. Am. Chem. Soc.等影响因子大于5的杂志上发表论文10篇,在影响因子为3到5之间的杂志上发表论文为76篇,在影响因子为23之间的杂志上的论文为131篇。实验室在如下5个方面取得了具有代表性阶段性成果:

 

  1. 具有抗癌、抗炎和抗疟活性的复杂天然产物的合成,结构-活性关系及作用机制研究方面的论文

  2. 一些生物大分子的选择性小分子调节剂的设计、合成及活性研究方面的论文

  3. 有机合成新反应和新方法的研究以及它们在复杂生物活性分子合成中的应用方面的论文

  4. 生物催化和生物转化方面的论文

  5. 酶和细胞色素等蛋白质的结构生物学研究方面的论文

     

 

4.生物催化和生物转化方面

论文24篇及他引数55次

 
序号
论 文 名 称
作 者
刊物名称
年卷
期页
他引次数
1
Enzymatic Synthesis of (R)-Cyanohydrins by Three (R)-Oxynitrilase Sources in Microaqueous Organic Medium
G. Lin, S.Han,Z. Li
Tetrahedron
1999, 55, 3531-3540
11
2
Purification, chracterization and structural study of the neuro-peptides from scorpion Buthus martensi Karsch
H. Wu, G. Wu,X. Huang, F. He,S. Jiang
Pure Appl.
Chem.
1999, 71, 1157-1162
5
3
Overexpression in Escherichia coli and Chara- cterization of the Chloroplast Triosephos-phate Isomerase from Spinach
G.i Tang,Y.Wang#,J. Biao#, H. Chen
Protein Expression and Purification
1999, 16,
432~ 439
 
4
Synthesis of perfluoroalkylated sugars catalyzed by rabbit muscle aldolase (RAMA)
W. Zhu,Z. Li
J.Chem.Soc.,Perkn Trans.1
2000
1105- 1108
1
5
Microbial Transformation of 2-Hydroxy and 2-Acetyoxy Ketones with Geotrichum sp
Z. Wei,G. Lin, Z. Li
Bioorg. &Med.
Chem.
2000,8,
1129~ 1137
8
6
Baker’s yeast mediated mono-reduction of 1,3- cyclo-hexanediones bearing two identical C(2) substituents
Z. Wei, Z. Li,
G. Lin
Tetrahedron:
Asymmetry
2001, 12,
229-233
1
7
(R)-Oxynitrilase-catalyzed hydrocyanation: the first synthesis of optically active fluorinated mandelonitriles
S. Han, P. Chen, G. Lin, H. Huang#, Z. Li
Tetrahedron:
Asymmetry
2001, 12,
843~846
7
8
Enantioselective hydrolysis of various racemic a -substituted arylacetoni- triles using Rhodoco- ccus sp. CGMCC 0497
Z.Wu,Z.Li
Tetrahedron:
Asymmetry
2001, 12, 3305-3312
1
9
Lipase-catalyzed regioselective acylation of diosgenyl saponins
B. Yu,,G.Xing, Y. Hui, X.Han#
Tetrahedron
Lett.
2001, 42, 5513-5516
3
10
Enantioselective Reduction of 2- Keto-3-Halo-alkane Phosphonates by Baker’s Yeast
C. Yuan,#K. Wang,#Z. Li
Heteroatom
Chem.
2001, 12, 551- 556
3
11
A Practical High Through-put Continuous Process for the Synthesis of Chiral Cyanohydrins
P. Chen,S.Hua, G. Lin, Z. Li
J. Org.Chem.
2002, 67, 8251-8253
1
12
Kinetic resolution of hydroxyalkanephosphonates catalyzed by Candida antarctica lipase B in organic media
Y. Zhang,#C.Yuan#, Z.Li
Tetrahedron
2002, 58, 2973-2978
4
13
Candida rugosa lipase-catalyzed enantioselec- tive hydrolysis in organic solvents. Convenient preparation of optically pure 2-hydroxy-2-aryl- ethanephosphonates
Y. Zhang,#Z.Li,C. Yuan#
Tetrahedron
Lett.
2002, 43, 3247-3249
1
14
Enhancement of enzyme activity and enantio- selectivity via cultivation in nitrile metabolism by Rhodococcus
Z. Wu, Z. Li
Biotechnol.
Appl.Biochem
2002, 35,
61-67
1
15
Enantioselective Reduction of Diakyl 4-(Dialk-oxyphosphoryl)-3- Oxobutanoates by Baker’s Yeast
C. Yuan,#K. Wang,J. Li#, Z. Li
Heteroatom
Chemistry
2002, 13,
153-156
1
16
Efficient Preparation of Highly Optically Active (S)-(-)-2,3-Allenols and (R)-(+)-2,3-Allenyl Acetates by a Clean Novozym-435-Catalyzed Enzymatic Separation of Racemic 2,3-Allenols
D. Xu,#Z. Li, S. Ma#
Chem. Eur. J
2002,8,
5012-5018
4
17
Enantioselective Hydrolysis of o-Nitrostyrene Oxide by Whole Cells of Aspergillus Niger CGMCC 0496
H. Jin,Z. Li
Biosci.
Biotechnol.
Biochem
2002, 66, 1123-1125
 
18
Enantioselective reduction of 2- ketoalkane-phosphonate by baker’s yeast
K. Wang, Z.Li,C. Yuan#
Phosphorus, Sulfur and Silicon
2002,177, 1797-1800
 
19
Biocatalytical kinetic resolution of hydroxy- alkanephosphonates
Y. Zhang,# Z. Li,C. Yuan#
Phosphorus, Sulfur and Silicon
2002,177, 2201-2202
 
20
Yeast-mediated regio- and stereo- selective reduction of dialkyl 2,4- dioxy-4-substituted butane- phosphonates
K. Wang,#J. Li,# Z. Li,C. Yuan#
Phosphorus, Sulfur and Silicon
2002,177, 2223-2224
 
21
Stereoslective Synthesis of Phosphorus Analogs of (R)-Carnitine and (R)-Gabob
C. Yuan,# K. Wang,#J. Li,# Z. Li
Phosphorus, Sulfur and Silicon
2002,177, 2391-2397
1
22
Highly enantioselective synthesis of a,a-disubstituted malonamic acids through asymmetric hydrolysis of dinitriles with Rhodococcus sp.CGMCC 0497
 
Z. Wu,Z. Li
CHEM.COMMUN.
2003
386-387
1
23
Practical synthesis of optically active a,a-disubstituted malonamic acids through asymmetric hydrolysis of malonamide derivatives with Rho- dococcus sp. CGMCC 0497
Z. Wu, Z. Li
J. Org. Chem.
2003, 68, 2479- 2482
1
24
Enantioselective biotransformation of a ,a-disubstituted dinitriles to the corresponding 2-cyanoacetamides using Rhodococcus sp. CGMCC 0497
Z. Wu, Z. Li
Tetrahedron: Asymmetry
2003, 14, 2133-2142
 

 

成果4前期研究工作部分论文4篇及其引用数59次

1

Lipase-catalyzed synthesis of a sugar ester con- taining arachidonic acid

 J

. Fang,Z. Li

Enzyme Microb.
Tech

1997

,20
52-56

 19

2

Production and characterisation of a biosurfactant isolated from Pseudomonas aeruginosa UW-1

 L. Sim,

Z. Li

J.Ind. Microbol & Biotech.

1997

,19,
232-238

 16

3

Synthesis of (R)-cyanohydrins by crude (R)-oxynitrilase-catalyzed reactions in micro-aqueous medium

 S. Han,

G. Lin, 
Z. Li

Tetrahedron:
Asymmetry

1998

,9
1835-1838

 13

4

Anti-Prelog microbial reduction of aryl alpha-halomethyl or alpha- hydroxymethyl ketones with Geotrichum sp 38

 Z. Wei,

Z. Li, G. Lin

Tetrahedron

1998

,54,
13059-13072

 11