BNPC生命有机化学国家重点实验室
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姓名:李昂(Ang Li)
职务:副主任,博导,研究员
E-mail:ali@sioc.ac.cn
电话:021-54925124
传真:021-
点击数:72318
课题组网站
 
研究方向
复杂天然产物全合成;
 
工作经历
2010.9至今     中国科学院上海有机化学研究所,研究员。
2010.1–2010.9   博士后研究员,新加坡化学与工程科学研究所,导师:Prof. K. C. Nicolaou
教育背景
2004.07–2009.11  博士,美国The Scripps Research Institute。导师:Prof. K. C. Nicolaou
2000.09–2004.07  理学学士,北京大学。导师:杨震教授
 
主要获奖情况
2017       Asian International Symposium Distinguished Lectureship Award, Chemical Society of Japan
2017       Tetrahedron Young Investigator Award for Organic Synthesis
2016       CAPA Biomatik Distinguished Faculty Award
2016       ChemComm Emerging Investigator Lectureship
2015       国家杰出青年基金资助
2015       药明康德生命化学研究奖
2015       Roche Chinese Young Investigators Award
2013       Asian Core Program Lectureship Award
2013       Chinese Chemical Society Wei-Shan Award for Synthetic Chemistry
2013       China Pharmaceutical Association–SERVIER Youth Medicinal Chemist Award
2013       Thieme Chemistry Journal Award
2012       Asian Core Program Lectureship Award
2009       Eli Lilly Graduate Fellowship
2007       国家优秀自费留学生奖学金
2007       Bristol-Myers Squibb Graduate Fellowship in Organic Synthesis
 
研究生教学
有机合成:
2018 有机合成五 一些形成C-C键的基本反应:自由基参与的反应
2018 有机合成五 一些形成C-C键的基本反应:烯基化
2018 有机合成六:周环反应 非直观DA
2018 有机合成六:电环化
2018 有机合成六:1,3-偶极环加成
2018 有机合成六:Sigmatropic重排
 
代表性论文

1.  W. Ye, A. Li,* A practical route to 3D molecular diversity, Nature 2018, 560, 314–316.

2.  Z. Lu, X. Zhang, Z. Guo, Y. Chen, T. Mu, A. Li,* Total synthesis of aplysiasecosterol A, J. Am. Chem. Soc. 2018, 140, 9211–9218.

3.  S. Zhou, R. Guo, P. Yang, A. Li,* Total synthesis of septedine and 7-deoxyseptedine, J. Am. Chem. Soc. 2018, 140, 9025–9029.

4.  W. Zhang, M. Ding, J. Li, Z. Guo, M. Lu, Y. Chen, L. Liu, Y.-H. Shen, A. Li,* Total synthesis of hybridaphniphylline B, J. Am. Chem. Soc. 2018, 140, 4227–4231.

5.  Y. Chen, W. Zhang, L. Ren, J. Li, A. Li,* Total syntheses of daphenylline, daphnipaxianine A, and himalenine D, Angew. Chem. Int. Ed. 2018, 57, 952–956.

6.  J. Li, W. Zhang, F. Zhang, Y. Chen, A. Li,* Total synthesis of longeracinphyllin A, J. Am. Chem. Soc. 2017, 139, 14893‒14896.

7.  Z. Zhang, J. Wang, J. Li, F. Yang, G. Liu, W. Tang, W. He, J.-J. Fu, Y.-H. Shen,* A. Li,* W.-D. Zhang,* Total synthesis and stereochemical assignment of delavatine A: Rh-catalyzed asymmetric hydrogenation of indene-type tetrasubstituted olefins and kinetic resolution through Pd-catalyzed triflamide-directed C−H olefination, J. Am. Chem. Soc. 2017, 139, 5558–5567.

8.  W. Zhang, A. Li,* A radical step forward, Nature Chemistry 2017, 9, 198–199.

9.  H. Li, Q. Chen, Z. Lu, A. Li,* Total syntheses of aflavazole and 14-hydroxyaflavinine, J. Am. Chem. Soc. 2016, 138, 15555–15558.

10.  P. Yang, M. Yao, J. Li, Y. Li, A. Li,* Total synthesis of rubriflordilactone B, Angew. Chem. Int. Ed. 2016, 55, 6964–6968.

11.  Y. Li, S. Zhu, J. Li, A. Li,* Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine, J. Am. Chem. Soc. 2016, 138, 3982–3985.

12.  M. Yang, X. Yang, H. Sun, A. Li,* Total Synthesis of Ileabethoxazole, Pseudopteroxazole, and seco-Pseudopteroxazole, Angew. Chem. Int. Ed. 2016, 55, 2851.

13.  Z. Lu, H. Li, M. Bian, A. Li,* Total Synthesis of Epoxyeujindole A, J. Am. Chem. Soc. 2015, 137, 13764–13767.

14.  S. Zhou, H. Chen, Y. Luo, W. Zhang, A. Li,* Asymmetric total synthesis of mycoleptodiscin A, Angew. Chem. Int. Ed. 2015, 54, 6878–6882.

15. M. Yang, J. Li, A. Li,* Total synthesis of clostrubin, Nature Communications 2015, 6, 6445.

16. Z. Meng, H. Yu, L. Li, W. Tao, H. Chen, M. Wan, D. J. Edmonds, J. Zhong, A. Li,* Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families, Nature Communications 2015, 6, 6096.

17. J. Li, P. Yang, M. Yao, J. Deng, A. Li,* Total synthesis of rubriflordilactone A, J. Am. Chem. Soc. 2014, 136, 16477–16480.

18.  Z. Lu, M. Yang, P. Chen, X. Xiong, A. Li,* Total synthesis of hapalindole-type natural products, Angew. Chem. Int. Ed. 2014, 53, 13840–13844.

19.  Y. Sun, P. Chen, D. Zhang, M. Baunach, C. Hertweck, A. Li,* Bioinspired total synthesis of sespenine, Angew. Chem. Int. Ed. 2014, 53, 9012–9016.

20.  J. Deng, S. Zhou, W. Zhang, J. Li, R. Li, A. Li,* Total synthesis of taiwaniadducts B, C, and D, J. Am. Chem. Soc. 2014, 136, 8185–8188.

21.  Y. Sun, R. Li, W. Zhang, A. Li,* Total synthesis of indotertine A and drimentines A, F, and G, Angew. Chem. Int. Ed. 2013, 52, 9201–9204.

22.  Z. Lu, Y. Li, J. Deng, A. Li,* Total synthesis of the Daphniphyllum alkaloid daphenylline, Nature Chemistry, 2013, 5, 679–684.

23.  M. Bian, Z. Wang, X. Xiong, Y. Sun, C. Matera, K. C. Nicolaou,* A. Li,* Total syntheses of anominine and tubingensin A, J. Am. Chem. Soc. 2012, 134, 8078–8081.

24.  J. Deng, B. Zhu, Z. Lu, H. Yu, A. Li,* Total synthesis of (–)-fusarisetin A and reassignment of the absolute configuration of its natural counterpart, J. Am. Chem. Soc. 2012, 134, 920–923.

 


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